Drug Standards
Apexbio Technology LLC Sarafloxacin HCl 91296-87-6 1g
Sarafloxacin hydrochloride (91296-87-6) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV It is designed to inhibit these essential enzymes thereby disrupting bacterial DNA replication Sarafloxacin hydrochloride exerts its biological activity primarily through stabilization of enzyme-DNA complexes leading to interference with bacterial DNA synthesis and cell death It demonstrates anti-microbial activity against various Gram-positive and Gram-negative bacterial strains with reported IC50 values against bacterial enzyme targets in the submicromolar range Based on these pharmacological properties sarafloxacin hydrochloride holds research potential in studies of bacterial resistance mechanisms susceptibility profiling and the pharmacodynamics of quinolone antibiotics
Apexbio Technology LLC Edoxaban tosylate monohydrate 1229194-11-9 50mg
Edoxaban tosylate monohydrate (CAS 1229194-11-9) is a small-molecule oral anticoagulant that selectively and directly inhibits coagulation factor Xa (FXa) a serine protease central to the thrombin generation pathway In vitro edoxaban tosylate monohydrate demonstrates high affinity for free FXa (Ki 0 561 nM) and the prothrombinase complex (Ki 2 98 nM) with over 10 000-fold selectivity for FXa versus related targets It effectively prolongs prothrombin time and activated partial thromboplastin time in human plasma without affecting platelet aggregation induced by ADP collagen or U46619 In vivo it exhibits dose-dependent inhibition of thrombosis in rodent models with minimal prolongation of bleeding time Edoxaban tosylate monohydrate is widely used in thrombosis and anticoagulation research
Apexbio Technology LLC Edoxaban tosylate monohydrate 1229194-11-9 10mg
Edoxaban tosylate monohydrate (CAS 1229194-11-9) is a small-molecule oral anticoagulant that selectively and directly inhibits coagulation factor Xa (FXa) a serine protease central to the thrombin generation pathway In vitro edoxaban tosylate monohydrate demonstrates high affinity for free FXa (Ki 0 561 nM) and the prothrombinase complex (Ki 2 98 nM) with over 10 000-fold selectivity for FXa versus related targets It effectively prolongs prothrombin time and activated partial thromboplastin time in human plasma without affecting platelet aggregation induced by ADP collagen or U46619 In vivo it exhibits dose-dependent inhibition of thrombosis in rodent models with minimal prolongation of bleeding time Edoxaban tosylate monohydrate is widely used in thrombosis and anticoagulation research
Sigma Aldrich Fine Chemicals Biosciences Dexamethasone acetate impurity E European Pharmacopoeia (EP) Reference Standard | 1524-94-3 |
Dexamethasone acetate impurity E European Pharmacopoeia (EP) Reference Standard | Mol Wt: 436.51 | 1524-94-3 |
Sigma Aldrich Fine Chemicals Biosciences Argatroban United States Pharmacopeia (USP) Reference Standard | 141396-28-3 | 350MG
Argatroban United States Pharmacopeia (USP) Reference Standard | Mol Wt: 526.65 | 141396-28-3 | 350MG
Sigma Aldrich Fine Chemicals Biosciences Vecuronium bromide Related Compound A United States Pharmacopeia (USP) Reference Standard | 13529-31-2 | 25MG
Vecuronium bromide Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 542.79 | 13529-31-2 | 25MG
Apexbio Technology LLC Nabumetone 42924-53-8 10mM (in 1mL DMSO)
Nabumetone (CAS 42924-53-8) is a non-steroidal anti-inflammatory compound that undergoes hepatic metabolism to yield its active form 6-methoxy-2-naphthylacetic acid (6-MNA) The active metabolite selectively inhibits cyclooxygenase (COX) particularly COX-2 resulting in reduced synthesis of prostaglandins involved in inflammation and pain signaling Nabumetone is commonly utilized in research to study prostaglandin-mediated inflammatory pathways COX enzyme function and the pharmacological modulation of inflammatory responses in preclinical models
Apexbio Technology LLC Lactulose 4618-18-2 50mg
Lactulose (4618-18-2) is a synthetic non-absorbable disaccharide composed of galactose and fructose units It is designed to reach the colon intact due to the absence of digestive enzymes in the upper gastrointestinal tract where it undergoes bacterial fermentation to form short-chain fatty acids primarily lactic and acetic acid thereby lowering intraluminal pH and increasing osmotic water retention Lactulose exerts its biological activity primarily through colonic acidification and modulation of water content by promoting fermentation-derived metabolite production No IC50 values have been reported for lactulose Based on these pharmacological properties lactulose holds research potential in studies investigating constipation mechanisms ammonia detoxification and the pathophysiology of hepatic encephalopathy
Sigma Aldrich Fine Chemicals Biosciences Cetirizine Related Compound G United States Pharmacopeia (USP) Reference Standard | 164726-80-1 | 50MG
Cetirizine Related Compound G United States Pharmacopeia (USP) Reference Standard | Mol Wt: 403.77 | 164726-80-1 | 50MG
Medchemexpress LLC Fluvoxamine (maleate) | 61718-82-9 | 99.8% | C19H25F3N2O6 | 5 MG
Fluvoxamine maleate is an antidepressant that functions pharmacologically as a selective serotonin reuptake inhibitor. This product is intended for research use only.
- Antidepressant compound
- Selective serotonin reuptake inhibitor (SSRI)
- Supplied as a solid
- White to off-white appearance
- Stable under recommended storage conditions
Sigma Aldrich Fine Chemicals Biosciences Oxymetazoline Related Compound A United States Pharmacopeia (USP) Reference Standard | 1391053-50-1 | 15MG
Oxymetazoline Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 314.85 | 1391053-50-1 | 15MG
Sigma Aldrich Fine Chemicals Biosciences Olanzapine Related Compound A United States Pharmacopeia (USP) Reference Standard | 138564-59-7 | 15MG
Olanzapine Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 259.28 | 138564-59-7 | 15MG
Sigma Aldrich Fine Chemicals Biosciences Zolmitriptan Related Compound A United States Pharmacopeia (USP) Reference Standard | 139264-35-0 | 20MG
Zolmitriptan Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 273.33 | 139264-35-0 | 20MG
Sigma Aldrich Fine Chemicals Biosciences Candesartan cilexetil Related Compound A United States Pharmacopeia (USP) Reference Standard | 139481-58-6 | 10MG
Candesartan cilexetil Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 468.51 | 139481-58-6 | 10MG